发明Compositions comprising neisseria meningitidis antigens from serogroups b and c

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著录项目

申请号 US20030148533 申请日 2003年03月10日 最早公开日 2005年04月07日 所属国家/地区 美国
公开号及公开日 授权日 1970年01月01日 说明书附图
申请人
发明人 GIULIANI MARZIA MONICA   PIZZA MARIAGRAZIA   RAPPUOLI RINO  
优先权 GB19990028196   19991129WO2000IB01940   20001129
专利分类号 A61K39/35   A61K39/05   A61K39/08   A61K39/395   A61K39/09   A61K39/40   A61K39/42   A61K39/095   A61K39/10   A61K39/102   A61K39/106   A61K39/116   A61K39/29   A61K39/385   A61P31/04  
代理机构 代理人

名称及摘要

组合物,包括奈瑟菌属 meningitidis 抗原从 serogroups b 以及 c
国际的专利申请书 wo99/61053 公开免疫组合物包含 n 。 meningitidis serogroup c 低聚糖共轭到载体,结合 n 。 meningitidis serogroup b 外膜蛋白质。 这些被公开在本应用结合还 neisserial 蛋白质和/或保护性抗原防其他病原生物(,例如,嗜血杆菌属 influenzae ,桌面出版, hbv ,等)。
Compositions comprising neisseria meningitidis antigens from serogroups b and c
International patent application WO99/61053 discloses immunogenic compositions that comprise N. meningitidis serogroup C oligosaccharide conjugated to a carrier, in combination with N. meningitidis serogroup B outer membrane protein. These are disclosed in the present application in combination with further Neisserial proteins and/or protective antigens against other pathogenic organisms (e.g. Haemophilus influenzae, DTP, HBV, etc.).

同族及引用

同族专利 (34) 引用其他专利(26) 被其他专利引用(36)

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Meningococcus adhesins
【Title of corresponding document:ep2191844A1】 Injectable vaccines against multiple meningococcal serogroups
【Title of corresponding document:ep1961426A1】
INJECTABLE VACCINES AGAINST MULTIPLE MENINGOCOCCAL SEROGROUPS
LIQUID VACCINES FOR MULTIPLE MENINGOCOCCAL SEROGROUPS
Vaccine
INJECTABLE VACCINES AGAINST MULTIPLE MENINGOCOCCAL SEROGROUPS
LIQUID VACCINES FOR MULTIPLE MENINGOCOCCAL SEROGROUPS
INJECTABLE VACCINES AGAINST MULTIPLE MENINGOCOCCAL SEROGROUPS
Compositions and methods for treating intracellular diseases
Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing CG motifs
Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
Liquid vaccines for multiple meningococcal serogroups
Vaccines for broad spectrum protection against Neisseria meningitidis
Helicobacter pylori vaccination
Process for production of Helicobacter pylori bacterioferritin
Helicobacter proteins and vaccines
Helicobacter pylori proteins useful for vaccines and diagnostics
GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
Helicobacter Pylori Vaccination
GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
Vaccines comprising aluminum adjuvants and histidine
Liquid vaccines for multiple meningococcal serogroups
GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
PROTEIN NMB0928 AND USE THEREOF IN PHARMACEUTICAL FORMULATIONS
IMMUNISING AGAINST MENINGOCOCCAL SEROGROUP Y USING PROTEINS
COMBINED VACCINES COMPRISING HEPATITIS B SURFACE ANTIGEN AND OTHER ANTIGENS
A vaccine composition comprsing a Haemophilus influenzae B polysaccharide conjugate antigen adsorbed onto aluminium phosphate
Combined vaccines comprising hepatitis B surface antigen, diphtheria, pertussis, tetanus antigens, and inactivated poliovirus antigens, and optionally haemophilus influenzae antigens
Urease-based vaccine and treatment for helicobacter infection
POLYSACCHARIDE FROM NEISSERIA MENINGITIDES CONTAINING MODIFIED GROUP B, CONJUGATED ANTIGEN, VACCINE AGAINST MENINGITIS GROUP B AND A METHOD OF INDUCTION OF ANTIBODY RESPONSE TO MENINGITIS OF GROUP B
Immunogenic conjugates
Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
OLIGOSACCHARIDE CONJUGATE VACCINES
Meningococcal class 1 outer-membrane protein vaccine
Compositions comprising the Tbp2 subunit of the transferrin receptor of Neisseria meningitidis
Preparation and uses of LOS-depleted outer membrane proteins of gram-negative cocci
Vaccine against gram negative bacteria
Vaccine against Gram-negative bacterial infections
Vaccine delivery system
Immunogenic conjugates comprising a Group B meningococcal porin and an H influenzae polysaccharide
Methods of immunizing adults using anti-meningococcal vaccine compositions
Neisseria meningitidis antigens and compositions
Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
Injectable vaccines against multiple meningococcal serogroups
Liquid vaccines for multiple meningococcal serogroups
Vaccines for broad spectrum protection against Neisseria meningitidis
ADJUVANT FORMULATION COMPRISING A SUBMICRON OIL DROPLET EMULSION
HIGH LEVEL EXPRESSION, PURIFICATION AND REFOLDING OF THE NEISSERIA MENINGITIDIS OUTER MEMBRANE GROUP B PORIN PROTEINS
PROTEINASE K RESISTANT SURFACE PROTEIN OF NEISSERIA MENINGITIDIS
VECTORS FOR GENE DELIVERY
EXPRESSION OF GROUP B NEISSERIA MENINGITIDIS OUTER MEMBRANE (MB3) PROTEIN FROM YEAST AND VACCINES
ADJUVANT FOR TRANSCUTANEOUS IMMUNIZATION
NOVEL SURFACE PROTEIN OF NEISSERIA MENINGITIDIS
NEISSERIAL ANTIGENS
MULTI-OLIGOSACCHARIDE GLYCOCONJUGATE BACTERIAL MENINGITIS VACCINES
BASB006 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM NEISSERIA MENINGITIS
NEISSERIA MENINGITIDIS ANTIGENS
NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS
COMBINATION MENINGITIDIS B/C VACCINES
COMBINATION NEISSERIAL COMPOSITIONS

法律状态历史( 到官方网站查询 )

2003年06月03日 us_as 转让(新专利权人: CHIRON SPA,ITALY
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:GIULIANI,MARZIA MONICA;PIZZA,MARIAGRAZIA;RAPPUOLI,RINO;REEL/FRAME:014123/0760;SIGNING DATES FROM 20020822 TO 20020829)
2003年11月05日 us_as 转让(新专利权人: CHIRON S.R.L.,ITALY
更多信息: CHANGE OF NAME;ASSIGNOR:CHIRON S.P.A.;REEL/FRAME:014699/0226
生效日期: 20021212)
2008年09月25日 us_as 转让(新专利权人: NOVARTIS VACCINES AND DIAGNOSTICS SRL,ITALY
更多信息: CHANGE OF NAME;ASSIGNOR:CHIRON SRL;REEL/FRAME:021595/0810
生效日期: 20060305)
2016年10月20日 us_as 转让(新专利权人: GLAXOSMITHKLINE BIOLOGICALS SA,BELGIUM
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:NOVARTIS VACCINES AND DIAGNOSTICS SRL;REEL/FRAME:040077/0483
生效日期: 20161020)

更新记录

2014年06月20日