发明Formulations containing substituted imidazole derivatives

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著录项目

申请号 US20050534117 申请日 2005年10月06日 最早公开日 2006年06月22日 所属国家/地区 美国
公开号及公开日 US2006134194A1   2006年06月22日
授权日 1970年01月01日 说明书附图
申请人 BANBURY SUSAN (美国)  
JUUJARVI PAIVI (美国)  
GROTHER LEON (美国)  
LUNSMANN WALTER (美国)  
MURRAY OWEN (美国)  
SAVOLA JUHA-MATTI (美国)  
发明人 BANBURY SUSAN   JUUJARVI PAIVI   GROTHER LEON   LUNSMANN WALTER   MURRAY OWEN   SAVOLA JUHA-MATTI  
优先权 GB20020026076   20021108WO2003US34934   20031103US20050534117   20051006
专利分类号 A61K9/20   A61K9/00   A61K31/4164   A61K47/26   A61K47/42  
代理机构 代理人

名称及摘要

制剂含有取代的咪唑衍生物
改进制剂含有取代的咪唑衍生物通式1,式 (i) ,其中 y 是- ch ≤;子>;2≤; O#- >;-或- Co -, r ≤;子>;1≤; O#- >;被 h ,卤代或羟基, r ≤;子>;2≤; O#- >;被 h 或卤代,以及 r ≤;子>;3≤; O#- 和成品率; s h 或低级烷基(,例如, c ≤;子>;1≤; O#- >;向 c ≤;子>;4≤; O#- >;烷基,优选 c ≤;子>;1≤; O#- >;或 c ≤;子>;2≤; O#- >;烷基),或药学上可接受的盐,例如酸加食盐,例如,氢氯化物,为化合物通式( i ),是固体快速-分散剂型,适合于预胃吸收。
Formulations containing substituted imidazole derivatives
Improved formulations containing substituted imidazole derivatives of the general formula 1, formula (I) wherein Y is -CH2- or -CO-, R1 is H, halo or hydroxy, R2 is H or halo, and R3 is H or lower alkyl (e.g. C1 to C4 alkyl, preferably C1 or C2 alkyl), or a pharmaceutically acceptable salt, such as an acid addition salt, e.g. the hydrochloride, of a compound of the general formula (I), are in solid fast-dispersing dosage form suitable for pre-gastric absorption.

同族及引用

同族专利 (19) 引用其他专利(6) 被其他专利引用(36)

GB0226076D0 Improved formulations containing substituted imidazole derivatives
CA2503630C IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
WO2004043439A1 IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
AU2003287476B2 Improved formulations containing substituted imidazole derivatives
NO336460B1 Improved formulations containing substituted imidazole derivatives
MXPA05004745A IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES.
KR101170548B1 IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
EP1581192B1 IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
PL214226B1 IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
RU2349305C2 ENHANCED FINISHED FORMULATIONS CONTAINING SUBSTITUTED IMIDASOL DERIVATIVES
US2006134194A1 Formulations containing substituted imidazole derivatives
US9717681B2 Formulations containing substituted imidazole derivatives
JP2006517516A 【Title of corresponding document:us2006134194A1】 Formulations containing substituted imidazole derivatives
NZ539731A Improved formulations containing substituted imidazole derivatives
IN232053A1 "a fast-dispersing solid dosage form"
JP5474033B2 IMPROVED FORMULATION CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVE
ES2392967T3 improved Formulations that contain derivatives of imidazol replaced
HK1080282A1 IMPROVED FORMULATIONS CONTAINING SUBSTITUTED IMIDAZOLE DERIVATIVES
IL168257A Formulations containing substituted imidazole derivatives
PROCESS FOR FORMULATING FAST DISPERSING DOSAGE FORMS COMPRISING AT LEAST ONE FISH GELATIN SELECTED ON THE BASIS OF MOLECULAR WEIGHT
【Title of corresponding document:CA2567830C】 PROCESS FOR FORMULATING FAST DISPERSING DOSAGE FORMS COMPRISING AT LEAST ONE FISH GELATIN SELECTED ON THE BASIS OF MOLECULAR WEIGHT
Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight
Fast disintegrating compositions of meloxicam
MANUFACTURING METHOD OF MASTER DISC FOR OPTICAL DISC, AND MASTER DISC FOR OPTICAL DISC
COMPOSITIONS FOR DRUG ADMINISTRATION
Tableted blood plasma microconcentrated coagulation reagents and method of making same.
INTRABUCCALLY DISINTEGRATING PREPARATION AND PRODUCTION THEREOF
SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE
INTRAORALLY RAPIDLY DISINTEGRABLE TABLET
Use of an acrylic-type polymer as desintregrating agent, process for making tablets and resulting tablets
Improved means for locking nuts
PHARMACEUTIAL DOSAGE FORMS
PRODUCTION OF MOLDED ARTICLE CARRING CHEMICAL SUBSTANCE AND PACKAGED ARTICLE CONTAINING SAME
TABLET HAVING FLEXIBILITY
【Title of corresponding document:CA2117305A1】 SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE
Fast-dispersing dosage forms containing fish gelatin
Articles for carrying chemicals
Rapidly dissoluble medicinal dosage unit and method of manufacture
Attenuation of ethyl alcohol intoxication with alpha-2 adrenoceptor antagonists
Fast dissolving dosage forms
Substituted imidazole derivatives and their preparation and use
FREEZE DRY COMPOSITION AND METHOD FOR ORAL ADMINISTRATION OF DRUGS, BIOLOGICALS, NUTRIENTS AND FOODSTUFFS
Rapidly distintegrating tablet
Process for preparing fast dispersing solid oral dosage form
Water soluble film for oral administration with instant wettability
Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
Means for creating a mass having structural integrity
Compositions and methods for mucosal delivery
Process for preparing solid dosage forms for unpalatable pharmaceuticals
Rapid-melt semi-solid compositions, methods of making same and method of using same
Fast-dissolving dosage forms for dopamine agonists
Galenic formulations fast disintegrating in the mouth and method for preparing same
Fast-dispersing dosage forms containing fish gelatin
EFFERVESCENT DOSAGE FORM AND METHOD OF ADMINISTERING SAME
SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE
INTRABUCCALLY DISINTEGRATING PREPARATION AND PRODUCTION THEREOF
ENANTIOMERS OF 4-(5-FLUORO-2,3-DIHYDRO-1H-INDEN-2-YL)-1H-IMIDAZOLE
GALENIC FORMULATIONS FAST DISINTEGRATING IN THE MOUTH AND METHOD FOR PREPARING SAME
A METHOD AND APPARATUS FOR MANUFACTURING DISSOLVABLE TABLETS
FAST-DISPERSING DOSAGE FORMS CONTAINING FISH GELATIN
GLUCAN BASED FILM DELIVERY SYSTEMS

法律状态历史( 到官方网站查询 )

2006年03月21日 us_as 转让(新专利权人: R.P. SCHERER TECHNOLOGIES,INC.,NEVADA
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BENBURY,SUSAN;JUUJARVI,PALVI;GROTHER,LEON;AND OTHERS;REEL/FRAME:017358/0732;SIGNING DATES FROM 20050428 TO 20050601)
2006年03月21日 us_as 转让(新专利权人: R.P. SCHERER TECHNOLOGIES,INC.,NEVADA
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BENBURY,SUSAN;JUUJARVI,PALVI;GROTHER,LEON;AND OTHERS;SIGNING DATES FROM 20050428 TO 20050601;REEL/FRAME:017358/0732)
2007年05月22日 us_as 转让(新专利权人: MORGAN STANLEY SENIOR FUNDING,INC.,NEW YORK
更多信息: SECURITY AGREEMENT;ASSIGNORS:PTS ACQUISITION CORP.;PTS INTERMEDIATE HOLDINGS LLC;CARDINAL HEALTH 400,INC.;AND OTHERS;REEL/FRAME:019323/0302
生效日期: 20070410)
2007年07月24日 us_as 转让(新专利权人: CATALENT USA WOODSTOCK,INC.,NEW JERSEY
更多信息: CHANGE OF NAME;ASSIGNORS:CARDINAL HEALTH 400,INC.;CARDINAL HEALTH 406,LLC;CARDINAL HEALTH 409,INC.;AND OTHERS;REEL/FRAME:019588/0622
生效日期: 20070619)
2007年07月24日 us_as 转让(新专利权人: CATALENT USA PACKAGING,LLC,NEW JERSEY
更多信息: CHANGE OF NAME;ASSIGNORS:CARDINAL HEALTH 400,INC.;CARDINAL HEALTH 406,LLC;CARDINAL HEALTH 409,INC.;AND OTHERS;REEL/FRAME:019588/0622
生效日期: 20070619)
2007年07月24日 us_as 转让(新专利权人: CATALENT PHARMA SOLUTIONS,INC.,NEW JERSEY
更多信息: CHANGE OF NAME;ASSIGNORS:CARDINAL HEALTH 400,INC.;CARDINAL HEALTH 406,LLC;CARDINAL HEALTH 409,INC.;AND OTHERS;REEL/FRAME:019588/0622
生效日期: 20070619)
2007年07月24日 us_as 转让(新专利权人: CATALENT USA PAINTBALL,INC.,NEW JERSEY
更多信息: CHANGE OF NAME;ASSIGNORS:CARDINAL HEALTH 400,INC.;CARDINAL HEALTH 406,LLC;CARDINAL HEALTH 409,INC.;AND OTHERS;REEL/FRAME:019588/0622
生效日期: 20070619)
2007年07月24日 us_as 转让(新专利权人: CATALENT PHARMA SOLUTIONS,LLC,NEW JERSEY
更多信息: CHANGE OF NAME;ASSIGNORS:CARDINAL HEALTH 400,INC.;CARDINAL HEALTH 406,LLC;CARDINAL HEALTH 409,INC.;AND OTHERS;REEL/FRAME:019588/0622
生效日期: 20070619)
2016年11月22日 us_as 转让(新专利权人: R.P. SCHERER TECHNOLOGIES,LLC,NEVADA
更多信息: CONVERSION;ASSIGNOR:R. P. SCHERER TECHNOLOGIES,INC.;REEL/FRAME:040670/0027
生效日期: 20090904)

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2014年06月20日