发明Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis

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著录项目

申请号 US20050544350 申请日 2005年11月18日 最早公开日 2006年06月15日 所属国家/地区 美国
公开号及公开日 US2006128800A1   2006年06月15日
授权日 说明书附图
申请人 PENNEY CHRISTOPHER (美国)  
GAGNON LYNE (美国)  
LAURIN PIERRE (美国)  
ZACHARIE BOULOS (美国)  
发明人 PENNEY CHRISTOPHER   GAGNON LYNE   LAURIN PIERRE   ZACHARIE BOULOS  
优先权 US20030445454P   20030207WO2004GB00457   20040206US20050544350   20051118
专利分类号 A61K31/255   A61K31/20   A61K31/225  
代理机构 代理人

名称及摘要

作为红细胞生成刺激剂的中链长脂肪酸类、甘油酯类和类似物
包括通式I、II、IIa、III和IIIa任一项的化合物或其组合的组合物在制备用于刺激红细胞生成的药物中的应用,其中:R1各自独立为C7-11烷基;A和B独立为H或CO-R1;R2为H或C1-4烷基;M为金属一价阳离子(k=1)或二价阳离子(k=2);Y为O或NH;且Z为O、NH、CH2O或键。优选该组合物进一步包括人红细胞生成素。
Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis
Use of a composition comprising a compound of any of formulae I, II, Ila, III and Illa; or a combination thereof wherein each R1 is independently C7-11 alkyl; A and B are independently H or CO-R1; R2 is H or C1-4 alkyl; M is a metal monocation (k=1) or dication (k=2); Y is 0 or NH; and Z is 0, NH, CH2O or a bond; for the manufacture of a medicament for stimulating erythropoiesis. Preferably, the composition further comprises human erythroporietin.

同族及引用

同族专利 (0) 引用其他专利(12) 被其他专利引用(25)

Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
Compositions capable of facilitating penetration across a biological barrier
Substituted Purinyl Derivatives With Immunomodulator And Chemoprotective Activity And Use Alone Or With Medium-Chain Length Fatty Acids Or Glycerides
Medium-chain length fatty alcohols as stimulators of hematopoiesis
COMPOSITIONS CAPABLE OF FACILITATING PENETRATION ACROSS A BIOLOGICAL BARRIER
Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer
PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY
Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
Pharmaceutical compositions and related methods of delivery
Pharmaceutical compositions and related methods of delivery
Use of fusion protein
TOPICAL FORMULATIONS AND USES
Dietary supplement utilizing omega -3/medium chain trigylceride mixtures
Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
Thixotropic formulations
Protein nanomatrixes and method of production
Absorption enhancement of antibiotics
Nutritive composition for prevention and therapy of infection diseases caused by immunosuppression
Method of stimulating hematopoiesis with hemoglobin
Method of promoting hair growth
Enternal composition for pediatric patients
Enhancing blood cell count with oxypurine nucleosides
Non-aqueous oral-drench compositions containing avermectin compounds
Oral liposomal delivery system
PRODUCTION OF MULTIVESICULAR LIPOSOMES
Fluidized polymer suspensions of cationic polysaccharides in emollients and use thereof in preparing personal care compositions
Erythropoietin liposomal dispersion
Clear oil-containing pharmaceutical compositions
JM216 formulations
Bubbling enteric coated preparations
Compositions of tocol-soluble therapeutics
Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life
Systemic administration of a therapeutic preparation
Inclining coffin
Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
Substituted Purinyl Derivatives With Immunomodulator And Chemoprotective Activity And Use Alone Or With Medium-Chain Length Fatty Acids Or Glycerides

法律状态历史( 到官方网站查询 )

2005年11月16日 us_as 转让(新专利权人: PROMETIC BIOSCIENCES INC.,CANADA
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:PENNEY,CHRISTOPHER;GAGNON,LYNE;LAURIN,PIERRE;AND OTHERS;REEL/FRAME:016788/0600
生效日期: 20051021)
2007年05月15日 us_as 转让(新专利权人: VENTURE LENDING & LEASING IV,INC.,CALIFORNIA
更多信息: SECURITY AGREEMENT;ASSIGNOR:PROMETIC BIOSCIENCES INC.;REEL/FRAME:019324/0585
生效日期: 20060927)
2013年07月18日 us_as 转让(新专利权人: PROMETIC BIOSCIENCES INC.,QUEBEC
更多信息: RELEASE BY SECURED PARTY;ASSIGNOR:VENTURE LENDING & LEASING IV,INC.;REEL/FRAME:030828/0109
生效日期: 20091005)
2016年03月28日 us_as 转让(新专利权人: PROMETIC PHARMA SMT LIMITED,UNITED KINGDOM
更多信息: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:PROMETIC BIOSCIENCES INC.;REEL/FRAME:038114/0510
生效日期: 20160328)

更新记录

2014年06月20日